First Author | Hanratty W P | Year | 1993 |
Journal | Mol Gen Genet | Volume | 238 |
Pages | 33-7 | PubMed ID | 8479437 |
Abstract Text | The Drosophila Tumorous-lethal (Tum-l) mutation acts as an activated oncogene, causing hematopoietic neoplasms, overproliferation, and premature differentiation. Tum-l is a dominant mutation in the hopscotch (hop) locus, which is required for cell division and for proper embryonic segmentation. The Tum-l temperature-sensitive period for melanotic tumor formation includes most of larval and pupal development. | Doi | 10.1007/BF00279527 |
Issue | 1-2 | Month | Apr |