| First Author | Chen Hai-Xu | Year | 2004 |
| Journal | FEBS Lett | Volume | 561 |
| Pages | 181-5 | PubMed ID | 15013774 |
| Abstract Text | Antibacterial peptides' genes are rapidly and transiently expressed on immune stimulation, which is the characteristic of immediate early genes. It implies post-transcriptional regulation is an important pathway in antibacterial peptides' gene expression. In a search of putative post-transcriptional regulatory elements, we found a segment of an AU-rich sequence in 3'-untranslated region (UTR) of drosophila diptericin mRNA. 3'-UTR of diptericin mRNA can be specifically bound with Elav and this binding can be competed with the typical AU-rich element (ARE) of c-fos mRNA. These results suggest that the AU-rich sequence in the 3'-UTR of diptericin mRNA may be a cis-acting element and involved in post-transcriptional regulation. | Doi | 10.1016/S0014-5793(04)00161-9 |
| Issue | 1-3 | Month | Mar |
