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Publication : Identification and characterization of a neuron-specific nuclear antigen in Drosophila.

First Author  Bier E Year  1988
Journal  Science Volume  240
Pages  913-6 PubMed ID  3129785
Abstract Text  An antigen found only in neuronal nuclei of Drosophila melanogaster is revealed by staining with a monoclonal antibody (Mab44C11). This antigen appears early in development, before neurons show any other signs of antigenic or morphologic differentiation, and persists throughout development. This nuclear staining permits reliable detection of neurons in developmental studies of wild-type and mutant flies. Protein immunoblot analyses and immune precipitation experiments show that the neuronal nuclear antigen is a 50-kilodalton polypeptide. Doi  10.1126/science.3129785
Issue  4854 Month  May

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