First Author | Soares Deividi C S | Year | 2018 |
Journal | Mol Cell Biochem | Volume | 442 |
Pages | 129-142 | PubMed ID | 28994023 |
Abstract Text | 2expression. Moreover, both 4AP- and PTZ-fed flies presented a significant decrease in MTT reduction, down-regulation, and inhibition of SOD in body. However, SOD was significantly more active in the head of both 4-AP and PTZ-treated flies. Our findings provide evidence regarding the toxicological potential of both PTZ and/or 4-AP to flies. This model will help in decoding the underlying toxicological mechanisms of the stated drugs. It will also help to properly investigate the therapeutic strategies and to counteract the drastic changes associated with both epileptogenic drugs. | Doi | 10.1007/s11010-017-3198-3 |
Issue | 1-2 | Month | May |