| First Author | Anderson James Melvin | Year | 2004 |
| Journal | Curr Opin Cell Biol | Volume | 16 |
| Pages | 140-5 | PubMed ID | 15196556 |
| Abstract Text | Across the animal kingdom the apical junction complex of epithelial cells creates both a permeability barrier and cell polarity. Although based on overlapping and evolutionarily conserved proteins, the cell-cell contacts of nematodes, flies and mammals appear to differ in morphology and functional organization. Emerging evidence shows that the selective pore-like properties of vertebrate and invertebrate barriers are created by the claudin family. Similarly, assembly of the barriers requires a conserved set of polarity-generating protein complexes, particularly the PAR protein complexes. | Doi | 10.1016/j.ceb.2004.01.005 |
| Issue | 2 | Month | Apr |
