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Publication : The intimate genetics of Drosophila fertilization.

First Author  Loppin Benjamin Year  2015
Journal  Open Biol Volume  5
PubMed ID  26246493 Abstract Text  The union of haploid gametes at fertilization initiates the formation of the diploid zygote in sexually reproducing animals. This founding event of embryogenesis includes several fascinating cellular and nuclear processes, such as sperm-egg cellular interactions, sperm chromatin remodelling, centrosome formation or pronuclear migration. In comparison with other aspects of development, the exploration of animal fertilization at the functional level has remained so far relatively limited, even in classical model organisms. Here, we have reviewed our current knowledge of fertilization in Drosophila melanogaster, with a special emphasis on the genes involved in the complex transformation of the fertilizing sperm nucleus into a replicated set of paternal chromosomes.
Doi  10.1098/rsob.150076 Issue  8
Month  Aug

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