| First Author | Kassis J A | Year | 1992 |
| Journal | Proc Natl Acad Sci U S A | Volume | 89 |
| Pages | 1919-23 | PubMed ID | 1311855 |
| Abstract Text | Vectors derived from the Drosophila P element transposon are widely used to make transgenic Drosophila. Insertion of most P-element-derived vectors is nonrandom, but they exhibit a broad specificity of target sites. During experiments to identify cis-acting regulatory elements of the Drosophila segmentation gene engrailed, we identified a fragment of engrailed DNA that, when included within a P-element vector, strikingly alters the specificity of target sites. P-element vectors that contain this fragment of engrailed regulatory DNA insert at a high frequency near genes expressed in stripes. | Doi | 10.1073/pnas.89.5.1919 |
| Issue | 5 | Month | Mar |
