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Publication : FUS interacts with ATP synthase beta subunit and induces mitochondrial unfolded protein response in cellular and animal models.

First Author  Deng Jianwen Year  2018
Journal  Proc Natl Acad Sci U S A Volume  115
Pages  E9678-E9686 PubMed ID  30249657
Abstract Text  mtgenes in FUS transgenic flies ameliorates neurodegenerative phenotypes. Our data show that mitochondrial impairment is a critical early event in FUS proteinopathy, and provide insights into the pathogenic mechanism of FUS-induced neurodegeneration. Doi  10.1073/pnas.1806655115
Issue  41 Month  10

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