| First Author | Ma Dingbang | Year | 2021 |
| Journal | Elife | Volume | 10 |
| PubMed ID | 33438579 | Abstract Text | Drosophilacircadian neurons, we optimized a single-cell RNA sequencing method and assayed clock neuron gene expression at different times of day. The data identify at least 17 clock neuron categories with striking spatial regulation of gene expression. Transcription factor regulation is prominent and likely contributes to the robust circadian oscillation of many transcripts, including those that encode cell-surface proteins previously shown to be important for cell recognition and synapse formation during development. The many other clock-regulated genes also constitute an important resource for future mechanistic and functional studies between clock neurons and/or for temporal signaling to circuits elsewhere in the fly brain. |
| Doi | 10.7554/eLife.63056 | Month | Jan |
