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Publication : CtBP modulates Snail-mediated tumor invasion in Drosophila.

First Author  Wu Chenxi Year  2021
Journal  Cell Death Discov Volume  7
Pages  202 PubMed ID  34349099
Abstract Text  V12/Sna-induced tumor invasion and Sna-mediated invasive cell migration. Furthermore, both CtBP and Sna are physiologically required for developmental cell migration during thorax closure. Finally, Sna activates the JNK signaling and promotes JNK-dependent cell invasion. Given that CtBP physically interacts with Sna, our data suggest that CtBP and Sna may form a transcriptional complex that regulates JNK-dependent tumor invasion and cell migration in vivo. Doi  10.1038/s41420-021-00516-x
Issue  1 Month  Aug

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