| First Author | Valdivia Mauricio | Year | 2017 |
| Journal | Front Cell Dev Biol | Volume | 5 |
| Pages | 26 | PubMed ID | 28386542 |
| Abstract Text | Drosophilatendon-cells to bear mechanical load depends on rearrangement of tendon cell cytoskeleton, thus studying the molecular mechanisms involved in this process is critical to understand the contribution of mechanical forces to the development of the musculoskeletal system. Here, we review recent findings regarding the role of chemical and mechanical signaling in myotendinous junction formation and tendon differentiation, and discuss molecular mechanisms of mechanotransduction that may allow tendon cells to withstand mechanical load during development of the musculoskeletal system. | Doi | 10.3389/fcell.2017.00026 |
