First Author | Karaiskos Nikos | Year | 2017 |
Journal | Science | Volume | 358 |
Pages | 194-199 | PubMed ID | 28860209 |
Abstract Text | DrosophilaVirtual Expression eXplorer (DVEX) database generates three-dimensional virtual in situ hybridizations and computes gene expression gradients. We used DVEX to uncover patterned expression of transcription factors and long noncoding RNAs, as well as signaling pathway components. Spatial regulation of Hippo signaling during early embryogenesis suggests a mechanism for establishing asynchronous cell proliferation. Our approach is suitable to generate transcriptomic blueprints for other complex tissues. | Doi | 10.1126/science.aan3235 |
Issue | 6360 | Month | 10 |