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Publication : Drosophilaembryo at single-cell transcriptome resolution.

First Author  Karaiskos Nikos Year  2017
Journal  Science Volume  358
Pages  194-199 PubMed ID  28860209
Abstract Text  DrosophilaVirtual Expression eXplorer (DVEX) database generates three-dimensional virtual in situ hybridizations and computes gene expression gradients. We used DVEX to uncover patterned expression of transcription factors and long noncoding RNAs, as well as signaling pathway components. Spatial regulation of Hippo signaling during early embryogenesis suggests a mechanism for establishing asynchronous cell proliferation. Our approach is suitable to generate transcriptomic blueprints for other complex tissues. Doi  10.1126/science.aan3235
Issue  6360 Month  10

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