| First Author | Qin X | Year | 1997 |
| Journal | Biochim Biophys Acta | Volume | 1350 |
| Pages | 136-40 | PubMed ID | 9048882 |
| Abstract Text | More than 3 kb of the human (h)IGFBP-4 gene 5'-flanking region was sequenced and assessed for promoter activity. The hIGFBP-4 promoter resides within a CpG island and demonstrates strong basal activity in human osteoblast-like osteosarcoma and COS-7 monkey kidney cells. Transient transfection of cells with hIGFBP-4 promoter-linked deletion constructs demonstrated that multiple cooperating cis-acting elements within 836 bp of the 5'-flanking region contributed to overall promoter strength. | Doi | 10.1016/s0167-4781(96)00220-5 |
| Issue | 2 | Month | Feb |
