help  | about  | cite  | software

Publication : amos, a proneural gene for Drosophila olfactory sense organs that is regulated by lozenge.

First Author  Goulding S E Year  2000
Journal  Neuron Volume  25
Pages  69-78 PubMed ID  10707973
Abstract Text  In a variety of organisms, early neurogenesis requires the function of basic-helix-loop-helix (bHLH) transcription factors. For the Drosophila PNS, such transcription factors are encoded by the proneural genes (atonal and the achaete-scute complex, AS-C). We have identified a proneural gene, amos, that has strong similarity with atonal in its bHLH domain. We present evidence that amos is required for olfactory sensilla and is regulated by the prepattern gene lozenge. Between them, amos, atonal, and the AS-C can potentially account for the origin of the entire PNS. Doi  10.1016/s0896-6273(00)80872-7
Issue  1 Month  Jan

Publication Annotations Displayer

30 Entities

23 Mesh Terms