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Publication : To bind or not to bind.

First Author  Biggin M D Year  2001
Journal  Nat. Genet. Volume  28
Pages  303-4 PubMed ID  11479583
Abstract Text  Gene expression is regulated by transcription factors binding selectively to particular portions of the genome. To what extent are these protein-DNA interactions influenced by the intrinsic sequence-specific recognition properties at each protein, and to what extent are they affected by other factors, such as chromatin structure or cooperative interactions with other proteins. Genome-wide surveys of DNA binding by transcription factors in vivo are beginning to provide some answers. Doi  10.1038/91045
Issue  4 Month  Aug

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