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Publication : Metabolite localization in living drosophila using High Resolution Magic Angle Spinning NMR.

First Author  Sarou-Kanian Vincent Year  2015
Journal  Sci Rep Volume  5
Pages  9872 PubMed ID  25892587
Abstract Text  We have developed new methods enabling in vivo localization and identification of metabolites through their (1)H NMR signatures, in a drosophila. Metabolic profiles in localized regions were obtained using HR-MAS Slice Localized Spectroscopy and Chemical Shift Imaging at high magnetic fields. These methods enabled measurement of metabolite contents in anatomic regions of the fly, demonstrated by a decrease in β-alanine signals in the thorax of flies showing muscle degeneration. Doi  10.1038/srep09872
Month  Apr

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