First Author | Sarou-Kanian Vincent | Year | 2015 |
Journal | Sci Rep | Volume | 5 |
Pages | 9872 | PubMed ID | 25892587 |
Abstract Text | We have developed new methods enabling in vivo localization and identification of metabolites through their (1)H NMR signatures, in a drosophila. Metabolic profiles in localized regions were obtained using HR-MAS Slice Localized Spectroscopy and Chemical Shift Imaging at high magnetic fields. These methods enabled measurement of metabolite contents in anatomic regions of the fly, demonstrated by a decrease in β-alanine signals in the thorax of flies showing muscle degeneration. | Doi | 10.1038/srep09872 |
Month | Apr |