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Publication : In Drosophila, female gonadal cells repress male-specific gene expression in XX germ cells.

First Author  Heller A Year  1998
Journal  Mech. Dev. Volume  73
Pages  203-9 PubMed ID  9622631
Abstract Text  In Drosophila, the sex of XX germ cells is determined by somatic signals. Whether sex-specific genes, however, are activated or repressed by somatic signals is not known. We have used mgm1, a germline-marker which is specifically expressed in male germ cells to analyze sex-specific gene expression of embryonic germ cells. We found that XX and XY germ cells that do not contact gonadal tissue can express mgm1. In contrast, XX germ cells that were associated with female somatic gonadal cells never expressed mgm1. Our results suggest that XX germ cells express male-specific genes, unless these genes are repressed by feminizing short range signals produced by the somatic cells of the prospective ovary. Doi  10.1016/s0925-4773(98)00053-7
Issue  2 Month  May

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