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Publication : Signal transduction in the early Drosophila embryo: when genetics meets biochemistry.

First Author  Perrimon N Year  1994
Journal  Trends Biochem. Sci. Volume  19
Pages  509-13 PubMed ID  7855897
Abstract Text  An elegant combination of genetic and biochemical approaches has been used to investigate a variety of signal transduction pathways in developmental processes. Here, we describe the 'terminal' signaling system in the Drosophila embryo, which is responsible for pattern formation in the polar regions of the embryo. This pathway involves a membrane-bound receptor tyrosine kinase (RTK) that is similar to other Drosophila RTKs, such as sevenless, and the mammalian RTKs, such as the epidermal growth factor or platelet-derived growth factor receptors. Issue  11
Month  Nov

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