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Publication : The Son of sevenless gene product: a putative activator of Ras.

First Author  Bonfini L Year  1992
Journal  Science Volume  255
Pages  603-6 PubMed ID  1736363
Abstract Text  The Son of sevenless (Sos) gene functions in signaling pathways initiated by the sevenless and epidermal growth factor receptor tyrosine kinases. The Sos gene has now been isolated and sequenced. Its product is a 1595-amino acid protein similar to the CDC25 protein in Saccharomyces cerevisiae, a guanine nucleotide exchange factor that activates Ras. These results imply a role for the ras pathway in Drosophila neuronal development. Issue  5044
Month  Jan

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