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Publication : Coordination of organ growth: principles and outstanding questions from the world of insects.

First Author  Andersen D S Year  2013
Journal  Trends Cell Biol. Volume  23
Pages  336-44 PubMed ID  23587490
Abstract Text  In animal species undergoing determinate growth, the making of a full-size adult body requires a series of coordinated growth events culminating in the cessation of growth that precedes sexual maturation. The merger between physiology and genetics now coming to pass in the Drosophila model allows us to decipher these growth events with an unsurpassed level of sophistication. Here, we review several coordination mechanisms that represent fundamental aspects of growth control: adaptation of growth to environmental cues, interorgan coordination, and the coordination of growth with developmental transitions. The view is emerging of an integrated process where organ-autonomous growth is coordinated with both developmental and environmental cues to define final body size. Doi  10.1016/j.tcb.2013.03.005
Issue  7 Month  Jul

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