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Publication : Gustatory receptors required for sensing umbelliferone in Drosophila melanogaster.

First Author  Poudel Seeta Year  2015
Journal  Insect Biochem. Mol. Biol. Volume  66
Pages  110-8 PubMed ID  26524963
Abstract Text  Studies of taste modality using the animal model Drosophila melanogaster have elucidated a number of uncharacterized mechanisms of sensory responses. Gustatory receptors expressed in taste organs are not only responsible for the acceptance and rejection of different foods, but are also involved in the process of selecting an oviposition site. This contact-chemosensation is essential for animals to discriminate between nutritious and contaminated foods. In this study, we characterized the function of gustatory receptors that play a dual role in feeding and oviposition using the plant metabolite umbelliferone. The combined electrophysiological and behavioral evidence demonstrated that two broadly tuned gustatory receptors, GR33a and GR66a, and one narrowly tuned gustatory receptor, GR93a, are all required to generate a functional umbelliferone receptor. Doi  10.1016/j.ibmb.2015.10.010
Month  Nov

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