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Publication : Genetic instability in Drosophila melanogaster: the genetics of an MR element that makes complete P insertion mutations.

First Author  Green M M Year  1986
Journal  Proc. Natl. Acad. Sci. U.S.A. Volume  83
Pages  1036-40 PubMed ID  3006025
Abstract Text  An MR element that maps to a specific locus in chromosome 3 of Drosophila melanogaster has the unusual feature of producing complete P (a mobile element) sequence mutations at several X chromosome loci. This MR also increases the frequency of mitotic recombination. Evidence is given for the transposition of MR. The complete P insertion mutations are autonomously unstable and are capable of causing otherwise stable incomplete (defective) P insertion mutations to revert. These results complement the analysis of P element functions with a synthetic complete P derivative. The genetic basis for the mutational-mitotic recombinational components of "hybrid dysgenesis"is conveniently explicable in terms of MR elements present in the genomes of flies present in the wild. Issue  4
Month  Feb

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