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Welcome to



the bioinorganic motif database

version 5.2 (July 2005)

COMe is an attempt to classify metalloproteins and some other complex proteins using the concept of bioinorganic motif.
A bioinorganic motif (BIM) may be defined as a common structural feature of a class of functionally related, but not necessarily homologous, proteins, that includes the metal atom(s) and first coordination shell ligands.

COMe is also...
Classification Of Metalloproteins COfactors and Metals COMplex proteins, etc.
Co-Ordination of Metals English word come (cf. GO) Italian word come (how)

Read the paper "COMe: the ontology of bioinorganic proteins" (BMC Structural Biology 4:3, 2004)

Discover more about the organisation of COMe and its XML format, or start browsing the relational implementation of the database from the top of the hierarchy, or through the Periodic Table, or list of Vitamins, or list of ENZYME cofactors, or...

You can query by COMe ID or using a case sensitive or insensitive text search...
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... or use our predefined queries ...
Choose a residue:
Choose a keyword:
... or have a look at the paths through the ontology
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COMe version 5.2 contains 524 BIM, 179 MOL and 1378 PRX (2081 entries)
Kirill Degtyarenko and Sergio Contrino

Last modified: Fri Jul 1 12:40:47 BST 2005